
Overview and History of ANADROMED 50
(Oxymetholone)
ANADROMED 50
(Oxymetholone) is known as one of the strongest oral anabolic
steroid available. The steroid-using bodybuilding community has been always
debated about ANADROMED 50
(Oxymetholone) and its main competitor DIANAMED 10
(Methandienone), which of these two steroids is stronger.
ANADROMED 50 is the trade name for the anabolic steroid more formally known as
Oxymetholone. Oxymetholone firstly was released in 1959 under the brand name
Anadrol. Almost immediately after it was launched, the pharmaceutical company
Syntex sold Oxymetholone under the name Anadrol-50 while Parke Davis & Co.
also manufactured it under the Androyd trade name. After its release onto
prescription markets, ANADROMED 50
(Oxymetholone) was quickly
started to be utilized for various medical
conditions ranging from geriatric atrophy to combating infections. It’s most
popular use as medication was in the treatment of anemia. ANADROMED 50 (Oxymetholone) was prescribed to increase the
red blood cell count and hemoglobin levels of the anemic individual. This
compound is a good help for such condition because
of its ability to stimulate
erythropoiesis at a very high rate. Although all anabolic steroids exhibit this
capability, ANADROMED 50
(Oxymetholone) ability to stimulate erythropoiesis are greater
than any other anabolic steroid.
Studies have shown that ANADROMED 50
(Oxymetholone) can
increase red blood cell production by a factor of 5 fold. ANADROMED 50
(Oxymetholone) is a very effective steroid for muscle-building purposes. Also, studies have
demonstrated that it has exerted notable anabolic effects on muscle-wasting
AIDS patients, causing them to gain 8kg of weight while those who were
administered a placebo not only lost weight but also experienced an increase in
mortality. Because of this important reason, ANADROMED 50
(Oxymetholone) is widely prescribed as prime medication for AIDS patients and muscle
wasting diseases.
Chemical Characteristics of ANADROMED 50
(Oxymetholone)
ANADROMED 50
(Oxymetholone) belongs to the family of Dihydrotestosterone (DHT) derived anabolic
steroids. Meaning, that ANADROMED 50
(Oxymetholone) is
Dihydrotestosterone modified. Other compounds in this ‘DHT family’ of anabolic
steroids include WINIMED 10 (Stanozolol), PRIMOMED 100 (Methenolone
Enanthate), MASTERMED E 200
(Drostanolone Enanthate), ANAVAMED 10 (Oxandrolone), as well as several others which are all derivatives of the
parent anabolic steroid DHT. All of the above mentioned DHT-derivative analogs
have the common factor, all of them are modified forms of DHT and thus DHT
could be considered the ‘parent’ or ‘progenitor’ hormone of these anabolic
steroids.
ANADROMED 50
(Oxymetholone) is different from its parent hormone DHT by the addition of a methyl group
attached to it, as well as a 2-hydroxymethylene group attached to a carbon in
the first cycloalkane ring of the steroid structure. Thanks to these modifications ANADROMED 50
(Oxymetholone) remains active in muscle tissue, which is where Dihydrotestosterone
would normally be rendered inactive by its reduction to other metabolites once
it enters muscle tissue. The enzyme responsible for doing this to
Dihydrotestosterone, which is present in large amounts in muscle tissue, is
3-hydroxysteroid dehydrogenase. With the chemical modifications mentioned, this
enzyme does not interact with ANADROMED 50 (Oxymetholone). This quality allows ANADROMED 50
(Oxymetholone) to be very active in muscle tissue and lends to its very strong potency.
ANADROMED 50
(Oxymetholone) possesses an anabolic rating of 320 (a little more than 3 times the
strength of Testosterone, with its anabolic rating of 100). ANADROMED 50
(Oxymetholone) also possesses reduced androgenic strength compared to that of
Testosterone, where ANADROMED 50
(Oxymetholone) holds an
androgenic rating of 45 (compared to Testosterone’s androgenic rating of 100).
ANADROMED 50
(Oxymetholone) contains the unique and unusual characteristics such as:
although it is a derivative of DHT, it possesses a very high level of
Estrogenic activity. It is typically
known that all DHT-derivative anabolic steroids should be unable to convert
into Estrogen via the aromatase enzyme and therefore no Estrogenic effects
could be present, but things are very different with ANADROMED 50
(Oxymetholone). ANADROMED 50
(Oxymetholone) is well known for causing water retention, bloating,
gynecomastia, and other Estrogenic side effects on the body even though it does
not convert into Estrogen. It is believed that ANADROMED 50
(Oxymetholone) itself acts as an estrogen in certain tissues. ANADROMED 50
(Oxymetholone) is infamous for its Estrogenic effects that every
potential user should be aware of. Those Estrogenic effects cannot be combated
with aromatase inhibitors due to its inability to convert into Estrogen.
ANADROMED 50
(Oxymetholone) is an orally active anabolic steroid, which means
it has been C17 Alpha Alkylated to allow the anabolic steroid to make the first
pass through the liver without suffering destruction through liver metabolism.
Also, ANADROMED 50
(Oxymetholone) is very well known for its very harsh hepatotoxicity. ANADROMED 50
(Oxymetholone) chemical modifications and chemical structure (including its C17 Alpha
Alkylation) make it very resistant to hepatic breakdown (liver metabolism). ANADROMED 50
(Oxymetholone) is regarded as the most liver toxic oral anabolic
steroid conventionally available.
ANADROMED 50 (Oxymetholone) Side Effects
ANADROMED 50
(Oxymetholone) is an orally active C-17 alpha-alkylated anabolic
steroid, which exhibits hepatotoxicity and negative effects on the liver.
Although ANADROMED 50
(Oxymetholone) possesses a chemical modification that is supposed
to reduce hepatotoxicity, in reality, ANADROMED 50
(Oxymetholone) still raises liver enzyme markers during use as
demonstrated in studies with HIV and AIDS patients. It is highly recommended to
limit the use of ANADROMED 50
(Oxymetholone) to cycle lengths of no greater than 4 – 6 weeks,
and to supplement with plenty of proven liver support compounds.
Being a DHT
(Dihydrotestosterone) derivative, ANADROMED 50
(Oxymetholone) does not convert into Estrogen. Still, Estrogenic
side effects are present with ANADROMED 50
(Oxymetholone), producing side effects such as bloating and water retention (often
reported as extreme) with concomitant increases in blood pressure, and the
development of gynecomastia. The use of a SERM (for example NOLVAMED 20 (Tamoxifen
citrate)) will mitigate gynecomastia, but it is not going to solve water
retention (and resultant blood pressure) issues.
Aromatase inhibitors will not work together
with ANADROMED 50
(Oxymetholone), because it has no interaction with the aromatase enzyme. There are
assumptions that ANADROMED 50
(Oxymetholone) may act as a Progestin causing these side effects,
but studies have demonstrated that ANADROMED 50
(Oxymetholone) does not
hold any Progestogenic properties. The most realistic explanation would be that
ANADROMED 50
(Oxymetholone) may
interact with the Estrogen receptor directly, or that a metabolite of ANADROMED 50
(Oxymetholone) might do
this as well.
But that is not all - sometimes ANADROMED 50 (Oxymetholone) has very strange side effects. For example, androgenic side
effects, which tend to be fairly reduced in comparison with Testosterone. ANADROMED 50 (Oxymetholone) does not convert into DHT and
instead is metabolized into 17-alpha-methyl dihydrotestosterone (Mestanolone).
Mestanolone is a stronger androgen, that is why some androgenic side effects
can be presented with ANADROMED 50
(Oxymetholone). This includes oily skin, acne, male pattern
baldness, benign prostatic hyperplasia, etc. The same like all other oral
anabolic steroids, ANADROMED 50
(Oxymetholone) tends to impact the cardiovascular system negatively in an extreme
manner, producing vast alterations in blood cholesterol profiles (for both LDL
and HDL).
ANADROMED 50 (Oxymetholone) Cycles and Use
ANADROMED 50
(Oxymetholone) cycles are
usually intended for bulking, strength-gaining, and general overall mass. ANADROMED 50
(Oxymetholone) cycles are not suited for cutting, fat loss, pre-contest,
or similar things. ANADROMED 50
(Oxymetholone) can be used as a help to accelerate fat loss; but it is a bad choice
because of its Estrogenic effects, such as water retention and bloating. The
aromatase inhibitor would also not work to reduce this bloating effect.
ANADROMED 50
(Oxymetholone) cycles are normally composed of ANADROMED 50
(Oxymetholone) as a
kickstarting compound for the first 4 – 6 weeks where it is supplementary to
other injectable base compounds that are used for similar purposes, such as TESTOMED E 250
(Testosterone Enanthate), DECAMED 250 (Nandrolone
Decanoate), TRENBOMED E 200
(Trenbolone Enanthate), etc. ANADROMED 50 (Oxymetholone) can be used in the middle of a
cycle to push through any stumbling blocks in training progress. Sometimes
users put ANADROMED 50
(Oxymetholone) in the end of a cycle in order to boost the end of a cycle and act as a
‘finisher’ compound in a cycle, leaving the user to end off their cycle with
some very impressive strength and size gains as they move into the PCT (Post
Cycle Therapy) phase.
ANADROMED 50
(Oxymetholone) cycles should not extend beyond 4 – 6 weeks because
of its hepatotoxicity issues. Other
compounds used with ANADROMED 50
(Oxymetholone), such as injectables, can be utilized beyond ANADROMED 50
(Oxymetholone) ending period.
Dosages and Administration of ANADROMED 50
(Oxymetholone)
ANADROMED 50
(Oxymetholone) dosage is varied and is dependent on the medical condition treated, as well
as constantly changing FDA guidelines. Medical dosages of ANADROMED 50
(Oxymetholone) are ranged from 2.5mg taken three times per day up to 30mg.
ANADROMED 50
(Oxymetholone) is most commonly manufactured in 50mg tablets. Therefore the dosage for
bodybuilding and athletic purposes is 25 – 50mg per day for a beginner.
Intermediate users are known for using a range of 50 – 100mg per day, and
advanced users take a high dose of 150mg per day (those users must be very
careful, as this dosage approaching risky limits). Most of the users, no matter
if that is beginner, intermediate, or advanced user, should seldom require more
than 50mg per day because of the strength of ANADROMED 50 (Oxymetholone) is an anabolic steroid.
Also, many users report a reduction in
appetite directly proportional to the dose utilized, and studies have shown
that ANADROMED 50
(Oxymetholone) increases glucose intolerance and insulin
resistance, thus making nutrient use by the body less efficient. ANADROMED 50
(Oxymetholone) dosages can and
should ideally be split throughout the day to ensure stable and steady blood
plasma levels of the hormone. ANADROMED 50
(Oxymetholone) exhibits a half-life of about 8 to 9 hours in the body, and therefore a
schedule involving a morning (AM) dose followed by an afternoon/evening (PM)
dose is best.
Chemical info /
Information
Oxymetholone (AKA Anadrol, Anadrol-50)
Chemical Name: 17β-hydroxy-2-hydroxymethylene-17-methyl-5α-androstan-3-one
Molecular Weight: 332.48
g/mol
Formula: C21H32O3
Original Manufacturer: Syntex
Elimination
half-life: 8 – 9 hours
Detection Time: 2 months
Anabolic Rating: 320
Androgenic Rating: 45
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