
Overview and History of WINIMED 10 (Stanozolol)
WINIMED 10 is the brand name for the anabolic steroid known as
Stanozolol. WINIMED 10 (Stanozolol) is the third most popular anabolic
steroid among bodybuilders and athletes. The first place belongs to DIANAMED 10
(Methandienone), while the second place is occupied by DECAMED 250 (Nandrolone
Decanoate).
WINIMED 10 (Stanozolol) is famous thanks to its use by
Canadian Olympic sprinter Ben Johnson in the 1988 Seoul Summer Olympic games
where he tested positive for it. Stanozolol was first described in
1959 when it was introduced to the
medical and scientific community. It was developed by Winthrop Laboratories in Great
Britain, and Sterling in the USA ended
up buying the patent in 1961 for the US market where it was branded as
Winstrol.
Winstrol was approved for medical
treatments, ranging from tissue and muscle wasting diseases to an Osteoporosis
drug; it also was used in the treatment of burn victims and children with
stunted growth. WINIMED 10 (Stanozolol) primary operation is through binding with the androgen
receptor rather than non-receptor mediated activity, which is common with
certain other anabolic steroids such as DIANAMED 10
(Methandienone) or ANADROMED 50
(Oxymetholone). WINIMED 10 (Stanozolol) also has a low affinity for binding with the
Glucocorticoid-binding sites in addition to some activity that is independent
of androgen receptors. Besides,WINIMED 10 (Stanozolol) possesses a very low degree of Progestogenic
activity in the body.
WINIMED 10 (Stanozolol) is truly unique compound because of its ability to
significantly lower SHBG (Sex Hormone Binding Globulin) levels in the body,
allowing freer Testosterone and other anabolic hormones to be able to exert
anabolic activity in muscle tissues. WINIMED 10 (Stanozolol) exhibits exceptional capability and a high degree of stimulating
and facilitating protein synthesis, also it possesses a capability of boosting
collagen synthesis in the body.
Chemical Characteristics of WINIMED 10 (Stanozolol)
WINIMED 10 (Stanozolol) chemical structure is very different from all other anabolic
steroids. WINIMED 10 (Stanozolol) is a derivative of Dihydrotestosterone (DHT) where it
contains a 3-2 Pyrazole group attached to the first cycloalkane ring (known as
the A-ring) of the anabolic steroid structure. The Pyrazole group's attachment
to the A-ring replaces the 3-keto group that usually sits in the same location.
Because of this major modification, WINIMED 10 (Stanozolol) is classified as a Heterocyclic steroid. The Pyrazole
group is responsible for WINIMED 10 (Stanozolol) stronger binding affinity for the androgen receptor
in muscle tissue.
Being a DHT-derivative
with modifications that separate its distinction with DHT, WINIMED 10 (Stanozolol) is more active in muscle tissue than DHT
itself which is rendered inactive almost immediately by two enzymes upon its
entrance into muscle tissue. All anabolic steroids that are part of the
DHT-derivatives family (such as WINIMED 10 (Stanozolol), ANAVAMED 10 (Oxandrolone), PRIMOMED 100 (Methenolone
Enanthate), Masteron, and others) contain modifications to their chemical
structures that grant them significant activity and effectiveness within muscle
tissue, where DHT itself unmodified would never survive metabolism there. WINIMED 10 (Stanozolol) contains
the methyl group (also known as C17-alpha alkylation)
to prevent it from being metabolized and broken down by the liver through oral
ingestion.
Properties of WINIMED 10 (Stanozolol)
WINIMED 10 (Stanozolol) main mechanism of action is the
binding with cellular androgen receptors. WINIMED 10 (Stanozolol) also contains some very small
measurable form of anti-Progestogenic properties thanks to the Progesterone
receptor. WINIMED 10 (Stanozolol) also possesses a low affinity for
Glucocorticoid-binding site interactions, as well as activity that is
independent of Androgen receptors, Progesterone receptors, and Glucocorticoid
receptors.
WINIMED 10 (Stanozolol) possesses a very high binding affinity for SHBG
(Sex Hormone Binding Globulin), this quality grants far more of WINIMED 10 (Stanozolol) to be free in the bloodstream in doing its
job of signaling muscle growth (together with other anabolic steroids that may
be stacked alongside it, such as Testosterone). SHBG is a protein that attaches
and binds to other sex hormones (Testosterone, Estrogen, or any synthetic
anabolic steroid) and renders them useless as long as SHBG is bound to that
hormone. SHBG places ‘handcuffs’ on any hormone it binds to and not allowing it
to do its job. WINIMED 10 (Stanozolol) has also demonstrated strong
suppression of SHBG production in the body.
Being a DHT-derivative, WINIMED 10 (Stanozolol) is unable to bind with the
aromatase enzyme, which is the huge benefit, because there will be no possible
Estrogen conversion. Meaning, this compound doesn't have Estrogen-related side
effects, such as water retention (and the associated risks of elevated blood
pressure), and others. Being a DHT-derivative, it is also not able to interact
with the 5-alpha-reductase enzyme, the enzyme which is responsible for the
conversion of Testosterone into Dihydrotestosterone.
WINIMED 10 (Stanozolol) exhibits a longer half-life
which is the result of its structural modifications, enabling its injectable
format to possess a half-life of approximately 24 hours and 9 hours for the
oral format.
WINIMED 10 (Stanozolol) holds an androgenic strength rating of 30 with an anabolic
strength rating of 320, meaning it holds over three times the anabolic strength
of Testosterone. Percentage-wise, it could be
described that WINIMED 10 (Stanozolol) is 320% more anabolic than
Testosterone, and it is 30% less androgenic than Testosterone. The injectable and oral formats of WINIMED 10 (Stanozolol) both possess the same chemical
structure and are exactly 100% identical to each other. Usually, that is not
like that.
All other anabolic steroids are different, where oral preparations are
always C17-alpha alkylated, and injectable preparations are absent of this
methylation (and often injectable compounds are also esterified to modulate the
release rate and half-life). The result is a greater amount of hepatotoxicity
(liver toxicity), and because both the injectable and oral preparations both
possess the hepatotoxic modification of C17-alpha alkylation, they both will
place an almost equal level of hepatotoxic strain on the liver. Anyway, the
injectable format avoids the first-pass through the liver, which allows it to
be slightly less hepatotoxic than the oral WINIMED 10 (Stanozolol) format.
WINIMED 10 (Stanozolol) Side Effects
Like any other
steroid, WINIMED 10 (Stanozolol) also contains side effects, such as hepatic (liver) issues relating to hepatotoxicity, HPTA (Hypothalamic
Pituitary Testicular Axis) disruption, and negative cardiovascular system
impacts. WINIMED 10 (Stanozolol) is a DHT-derived anabolic steroid it cannot
convert into Estrogen at any dose.
WINIMED 10 (Stanozolol) possesses a weaker androgenic strength rating
comparing to Testosterone, but androgenic side effects can still appear to
users who are especially sensitive to androgens. Androgenic side effects
include increased oily skin and acne, hair growth on the body, MPB (male
pattern baldness), and BPH (Benign Prostatic Hypertrophy). The use of a
5-alpha-reductase (5AR) inhibitor, such as Finasteride, Dutasteride, Proscar,
or Propecia wouldn’t be effective because WINIMED 10 (Stanozolol)does not convert into DHT.
HPTA suppression and Hepatotoxicity (liver toxicity) are also concerns, which should be taken
into account during the use of WINIMED 10 (Stanozolol). It is therefore recommended to use WINIMED 10 (Stanozolol), especially the oral variant, for periods of no longer than
6 – 8 weeks at a time. Cardiovascular health concerns are the major issue
regarding WINIMED 10 (Stanozolol) side effects, as it can stimulate cardiac
hypertrophy at even small dosages.
WINIMED 10 (Stanozolol) is infamous for producing very
dangerous negative alterations in blood cholesterol levels, even with miniscule
dosages of the oral format (as low as 6mg/day). Also, the injectable
preparation of Stanozolol has demonstrated very negative implications for
blood cholesterol.
WINIMED 10 (Stanozolol) Cycles and Use
WINIMED 10 (Stanozolol) cycles are normally held for fat loss,
cutting, and pre-contest preparation where the end goal is to achieve very low
body fat levels and a high level of definition in the physique. Some of the
users utilize WINIMED 10 (Stanozolol) for bulking, mass and strength gaining, but
there are other anabolic steroids which are the better choice for these
purposes. WINIMED 10 (Stanozolol) cycles normally include a base
compound of similar use, usually such as TESTOMED P 100
(Testosterone Propionate) for an 8 – 10-week cycle.
Intermediate and advanced WINIMED 10 (Stanozolol) cycles can involve three
compounds in total, normally a stack such as TESTOMED P 100
(Testosterone Propionate), TRENBOMED A 100
(Trenbolone Acetate) and any format of WINIMED 10 (Stanozolol). It is very important to
understand that because of the hepatotoxicity differences between the oral and
injectable WINIMED 10 (Stanozolol)formats, it is possible to run
its cycles longer with the injectable than the oral (8 – 10 weeks for the
injectable and 6 – 8 weeks for the oral respectively).
Dosages and Administration of WINIMED 10 (Stanozolol)
WINIMED 10 (Stanozolol) is a very versatile anabolic steroid, and its dosages of the oral
and injectable formats may vary extensively. In the medical field WINIMED 10 (Stanozolol) dosages usually are a 6mg per day, ideally
split up throughout the day (e.g. a 2mg tablet administered 3 times per day).
The injectable WINIMED 10 (Stanozolol) is typically prescribed at a
dosage of 50mg only once every two to three weeks. In case WINIMED 10 (Stanozolol) is utilized for athletics and
performance enhancement, such medical dosages and frequencies do not help at
all.
For athletics, physique, and strength, WINIMED 10 (Stanozolol) dosages range (for injectable
format) around 50 – 100mg administered every other day, equating to around 200
– 400mg per week. For oral WINIMED 10 (Stanozolol) format, the dosages are around
60mg per day, and lower dosages of WINIMED 10 (Stanozolol) (such as 25 – 50mg per day) are known to work
well for all groups of users and athletes.
For female users, 5 – 10mg per day of the oral format of WINIMED 10 (Stanozolol) is known to be pretty common. Such dosage is popular among female
bodybuilders and athletes that want to avoid any risk of virilization and other
unpleasant side effects. Although the injectable format of WINIMED 10 (Stanozolol) is not very popular among
female athletes and bodybuilders, 15mg injected every other day (for an
approximate total of 60mg per week) is a good recommendation.
Chemical info /
Information
Winstrol (AKA Stanozolol)
Chemical Name: 17β-Hydroxy-17-methyl-5alpha-androstano[3,2-c]pyrazole
Molecular Weight: 328.49
g/mol
Formula: C21H32N2O
Original Manufacturer: Winthrop
Laboratories
Elimination
half-life: 9 hours (oral), 24 hours
(injectable)
Detection Time: 2 months
Anabolic Rating: 320
Androgenic Rating: 30