Overview and History of CYTOMED 25 (Liothyronine Sodium (T3))

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CYTOMED 25 is a trade name for T3, which is Liothyronine Sodium. Liothyronine Sodium is a synthetic variant of thyroid hormone. The human body produces its natural thyroid hormone, which is known as triiodothyronine.  It must be noted that the human body's own natural endogenously manufactured thyroid hormone is known as Triiodothyronine, is different from Liothyronine Sodium. Although Liothyronine and triiodothyronine are two almost identical substances, Liothyronine is stronger and is also better absorbed through oral use. Liothyronine is the L-isomer of Triiodothyronine.

That is the reason why the Liothyronine sodium has been developed into a prescription medicine and preparation known as Cytomel, Tiromel, Tertroxin, etc. In the field of medicine, CYTOMED 25 (Liothyronine Sodium (T3)) is used to treat hypothyroidism, which is a condition in which the thyroid gland does not exclude the right and normal hormone levels for the proper function of the body. In that case, hypothyroidism is commonly diagnosed via a blood test that analyzes the serum hormone profile of thyroid hormones (T3, T4, and TSH, which is Thyroid Stimulating Hormone). Hypothyroidism also contains various symptoms such as a lack of energy, lethargy, weight and fat gain, hair loss, and alterations in skin color and texture.

T3 is the primary thyroid hormone used by the body. That is sad, but T3 hormone has a bad reputation among the bodybuilding and athletic community because of a lot of rumors and mysticism are surrounding this compound. A lot of different and false information circulated in regards to what it does, its use, and how it should be used. At the end of the day, many users within the anabolic steroid using community have become very afraid of T3, and don’t even want to try to use it.

Let us clarify those moments. T3 was originally developed as medicine by way of an extract from the thyroid gland. Many hormonal medicines originated exactly in the same way, as being derived from the endocrine glands from the cadavers of animals and humans.

The very first appearance of thyroid extract was administered in 1981 to an individual who suffered from myxedema, which is a skin disorder that is normally the result of hypothyroidism. Thyroid hormones were a pioneer – that is one of the first hormonal medicines used in the field of endocrinology and the treatment of many disorders and diseases. In the beginning, the very first thyroid extracts contained not only T3 hormone, but also T4, and these extracts were utilized for over 60 years in medicine.

Back in the 1950s, methods of creating thyroid hormones synthetically took over and the previously used thyroid extracts were done away with. Liothyronine Sodium (T3) and Levothyroxine Sodium (T4) are the two most popular currently used synthetic thyroid hormones. They are widely available in the United States and internationally.

The same like many other ancillary bodybuilding drugs, T3 is widely available in most countries worldwide with very little or no laws regarding its sale, distribution and purchase. It is manufactured by dozens of different pharmaceutical companies across the world under the different brand and trade names, as well as a diverse selection of generic T3 products. Because of all these reasons, it is not uncommon to find a wide variation in different T3 dosages in the different products. For example, T3 can commonly be seen in concentrations ranging from 5mcg, 25mcg, and up to 50mcg tablets.

Chemical Characteristics of CYTOMED 25 (Liothyronine Sodium (T3))

T3 (Liothyronine Sodium) is a synthetic variant of the body’s thyroid hormone Triiodothyronine.

Properties of CYTOMED 25 (Liothyronine Sodium (T3))

T3 hormone in the body is responsible for regulating the uptake of various nutrients into cells and into the mitochondria of those cells to effectively become used for the production and consumption of energy.  The mitochondria of every single cell in the body utilize carbohydrates (primarily), fat, and even protein for the production of an energy source known as ATP (Adenosine Triphosphate). Through the admission of more T3 hormone, this production of ATP will increase, leading to an increased rate of energy consumption in the form of fats, carbohydrates, and protein. This is the reason why the consumption of too much T3 hormone without the use of anabolic steroids can result in muscle loss. Bodybuilders and athletes like to use T3 as a physique and/or performance-enhancing drug because of its capability to distinctly boost the body's metabolism in the effort to metabolize body fat at a greater rate. T3 is traditionally used during cutting, dieting, and/or pre-contest phases of training due to the universal goal of these phases to break down body fat, though in recent years CYTOMED 25 (Liothyronine Sodium (T3)) became popular as a useful compound during bulking and mass gaining phases of training (normally in conjunction with anabolic steroids) in order to better efficiently process nutrients and/or to keep body fat levels down during periods of higher caloric intake.

CYTOMED 25 (Liothyronine Sodium (T3)) is commonly used with anabolic steroids due to its significant impact on the body’s metabolism as a whole. It is crucial to know that T3 is indiscriminate in its metabolism-boosting properties – it will increase the metabolism of fats, carbohydrates, and protein all equally. Meaning that, beyond a particular dose of T3, there is an increased risk of muscle loss through increased turnover of protein. When the user utilizes anabolic steroids together with a properly adjusted diet, this muscle loss as a result of T3 can be prevented as a result of the nitrogen-retaining and protein sparing properties of the anabolic steroids. CYTOMED 25 (Liothyronine Sodium (T3)) is often combined with other fat loss agents to increase its overall effect, as it does work synergistically with other fat loss agents. Some of these include Ephedrine, Clenbuterol, Albuterol, Human Growth Hormone (HGH) as well as other fat burning agents.

Medical CYTOMED 25 (Liothyronine Sodium (T3)) Dosage

CYTOMED 25 (Liothyronine Sodium (T3)) dosage for the treatment of hypothyroidism, is that of a starting dose of 25mcg per day. Following this, the user should notice his or her reactions and tolerance to the drug and adjusts their CYTOMED 25 (Liothyronine Sodium (T3)) dosage by no more than 25mcg per day. The average maintenance T3 doses lie between 25 – 75mcg per day. Once the patient’s level of desired optimal dose is achieved, this does remain steadily administered till the end of the treatment.

CYTOMED 25 (Liothyronine Sodium (T3)) Dosage For Fat Loss

Bodybuilders and athletes who want to use T3 for its weight loss and fat loss effects normally starts with a T3 dosage of 25 – 50mcg per day. Again, users should see how they react to the treatment. Tolerance relates to the experience of metabolism and fat burning effects, as well as the temperature increase associated with it. Every user is different and will respond in a different manner and a different intensity to anyone given CYTOMED 25 (Liothyronine Sodium (T3)) dosage, so it must be understood that a T3 dose of 50mcg for one individual might elicit steady fat loss, but that same 50mcg dose might not do very much for another.

Once tolerance is assessed after remaining at a 50mcg dose for a day or two, the user should then increase their CYTOMED 25 (Liothyronine Sodium (T3))  dosage by an additional 25mcg every day (or every other day, depending on the individual’s experience) until a peak optimal dose is achieved. The typical peak dose for most male bodybuilders and athletes lie in the range of 75 – 100mcg per day. Some individuals even utilized a high dose of 125mcg per day, though this is on the high end and is not recommended.

Female CYTOMED 25 (Liothyronine Sodium (T3)) Dosage

On average, the female users' response to the effects of CYTOMED 25 (Liothyronine Sodium (T3)) is the same as the male response. The only major difference in CYTOMED 25 (Liothyronine Sodium (T3)) dosage for female users is that of the difference in body weight and mass. Females tend to be of lower total size, weight, and body mass than men and therefore may tend to be more sensitive to a given T3 dosage. The highest effective dose for most female users should be in the range of approximately 50 – 75mcg per day, with 75mcg being at the uppermost high end.


Chemical info / Information
Liothyronine Sodium (AKA Cytomel, T3, Tertroxin, Tiromel, Thyroid hormone)
Chemical Name: sodium (S)-2-amino-3-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]propanoate
Molecular Weight: 672.96 g/mol
Formula: C15H11I3NNaO4
Original Manufacturer: ICI
Elimination half-life: 2.5 days
Detection Time: Cannot be detected via urinalysis
Anabolic Rating: N/A
Androgenic Rating: N/A