Overview and History of DECAMED 250 (Nandrolone Decanoate)

DECAMED 250 (Nandrolone Decanoate) is the brand for the anabolic steroid and parent hormone  Nandrolone. Specifically, DECAMED 250 (Nandrolone Decanoate) is the trade name for Nandrolone Decanoate – the decanoate ester variant of Nandrolone. Deca-Durabolin, more widely known as "Deca", is one of the most popular injectable anabolic steroids among bodybuilders. It is the second most popular and widely used anabolic steroid. First place is held by DIANAMED 10 (Methandienone), and third place is held by WINIMED 10 (Stanozolol). DECAMED 250 (Nandrolone Decanoate) is very popular not only among bodybuilders and athletes but that is also highly regarded among the medical establishment.
Nandrolone Decanoate was developed by the pharmaceutical company Organon in the 1960s. Nandrolone-Decanoate is a 19-nor anabolic steroid, with Nandrolone being the steroid attached to the massive Decanoate ester. The decanoate ester grants Nandrolone a much longer half-life of approximately 15 days. Being one of the first developed anabolic steroids, in 1962 Nandrolone was released onto the prescription drug market as Deca-Durabolin. DECAMED 250 (Nandrolone Decanoate) can be used during a cutting cycle, but its primary function is to add mass. Other functions of this steroid include the increase of hemoglobin and red blood cells, as well as promoting nitrogen retention.

DECAMED 250 (Nandrolone Decanoate) s widely used as a medicinal drug among as well it gained popularity among bodybuilders and athletes for its purportedly ‘mild’ nature. In terms of anabolism, DECAMED 250 (Nandrolone Decanoate) is only slightly stronger than Testosterone, with a strength rating of 125. By comparison, Testosterone’s anabolic strength rating is 100.

DECAMED 250 (Nandrolone Decanoate) possesses a very low androgenic rating of 37, making it favorable for those who are either sensitive to or with to avoid androgenic side effects. Additionally to all mentioned characteristics, Nandrolone possesses very low Estrogenic activity and binds very poorly with the aromatase enzyme, which is the enzyme responsible for the conversion of androgens into Estrogen. Again, comparing to Testosterone's conversion rates, only about 20% of Nandrolone is converted into Estrogen. The fact that like all other 19-nor compounds are, DECAMED 250 (Nandrolone Decanoate)   is also a Progestin, is what contributes to this low estrogenic activity.

Nandrolone also experiences aromatization into Estrogen in the liver, but it is considerably resistant in areas of the body where there is normally a high degree of Estrogen conversion (in fat tissue, for instance). Besides, being a Progestin, DECAMED 250 (Nandrolone Decanoate) express an affinity for the Progesterone receptor. This can present the risk of side effects and issues that are unique to 19-nor compounds and are unseen in most other anabolic steroids. DECAMED 250 (Nandrolone Decanoate) claimed to be good for the joints and bone tissue, which is indeed true. At the same time there exist a lot of myths and incorrect information among athletes and bodybuilders. DECAMED 250 (Nandrolone Decanoate) does not “lube the joints”, “store water in connective tissue and joints”, and doesn’t have any other such nonsense characteristics. Nandrolone promotes very significant increases in collagen synthesis, more so than most other anabolic steroids. Other studies have proved an ability for DECAMED 250 (Nandrolone Decanoate) to promote vast increases in bone mineral content. All of the above-mentioned means that bodybuilders and athletes can experience positive effects on connective and joint tissue, strengthening them during bulking, strength gaining, and mass gaining cycles. It allows them to lift heavier weight with an enhanced recovery of bone and connective tissue and gives a greater tolerance to the stressors on joints and bone that are produced by intense exercise and resistance training.

DECAMED 250 (Nandrolone Decanoate) Side Effects

In terms of side effects, compared to other compounds DECAMED 250 (Nandrolone Decanoate) is known as a very ‘mild' anabolic steroid. That is not 100% true – today we know much more information about DECAMED 250 (Nandrolone Decanoate) and understand that it is both a mild and harsh anabolic steroid, possessing both such properties. One is true - DECAMED 250 (Nandrolone Decanoate) experiences a very low aromatization rate into Estrogen, making estrogenic side effects less of an issue compared to other anabolic steroids. Of course, Estrogen-related side effects are not totally eliminated. Although they are still present, they are more manageable and users should therefore still be conscious of this fact. Estrogenic side effects can include bloating, water retention, blood pressure increases as a result of water retention, and gynecomastia. Users also shouldn’t ignore the fact that as a Progestin, DECAMED 250 (Nandrolone Decanoate) can also increase Prolactin levels in the body. All of the Progesterone and Prolactin related issues can result in the form of side effects that are very similar to Estrogen – puffy nipples, gynecomastia, bloating, etc. Anti-estrogens together with aromatase inhibitors are known for combating these side effects effectively even if they are attenuated through the Progesterone receptor. Studies have shown that the use of vitamin B6 is effective in order to control Prolactin levels (using 600mg daily). Anti-prolactin drugs such as Cabergoline and Bromocriptine are also very effective at reducing elevated Prolactin levels and are often the first line of treatment in case of Prolactin issues. As with all injectable steroids, nandrolone decanoate is easier on the liver compared to the oral anabolic steroids such as  Anadrol, Anavar, trenbolone, and DIANAMED 10 (Methandienone).

DECAMED 250 (Nandrolone Decanoate) does express a small degree of androgenic effects, and therefore the same as its estrogenic properties is less of a concern but should still be monitored and kept in mind. Several Androgenic side effects can appear, including increased oily skin and acne, increased bodily and facial hair growth, increased risk of male pattern baldness (MPB), and an increased risk of benign prostatic hyperplasia (BPH). Nandrolone also has side effects that are common among all anabolic steroids: disruption and/or shutdown of the HPTA (Hypothalamic Pituitary Testicular Axis), and negative cardiovascular implications.

For a long period of time, DECAMED 250 (Nandrolone Decanoate) was cited as an anabolic steroid that was mild on its impact on the HPTA and natural endogenous Testosterone levels. This is not true as studies have demonstrated that even a single 100mg injection of DECAMED 250 (Nandrolone Decanoate) per week, is all it takes to suppress endogenous Testosterone production rapidly reached close to 60%, and even higher (and faster) when larger dosages of DECAMED 250 (Nandrolone Decanoate) are used. For this reason, it is necessary that you supplement with some form of exogenous testosterone when you supplement with the Nandrolone compound. Not doing so will result in a low testosterone condition, and this is simply very bad for your health.

DECAMED 250 (Nandrolone Decanoate) can increase HDL (High-Density Lipoproteins, better known as your bad cholesterol) cholesterol levels. If your HDL levels are high the risk of cardiovascular conditions including heart disease and stroke increase. That is very important to keep your HDL levels under control, especially if you're running Nandrolone Decanoate stacks with an aromatase inhibitor. Moreover, when it is compared with Testosterone, Nandrolone tends to exhibit far worse negative cholesterol alterations on average. Recently published data have demonstrated that DECAMED 250 (Nandrolone Decanoate) is 11 times more damaging to blood vessels than Testosterone.

DECAMED 250 (Nandrolone Decanoate) Cycles and Use

DECAMED 250 (Nandrolone Decanoate) is widely used by most athletes and bodybuilders for bulking, mass-adding, and strength-gaining cycles. This is so due to its positive and beneficial effects on connective and bone tissue, allowing a greater rate of healing in these areas and an added injury preventative when heavier weights are used and more intense physical activity is engaged in. DECAMED 250 (Nandrolone Decanoate) is a long-acting long estered variant of Nandrolone (possessing a half-life of 15 days), therefore the cycles of DECAMED 250 (Nandrolone Decanoate) should be at least 12 weeks in length. DECAMED 250 (Nandrolone Decanoate) is often combined with similar long-estered compounds, such as Testosterone Cypionate.

Because its a slow reacting steroid most users will not experience the ‘kick-in’ of the compound until at least several weeks into the cycle, and this is where many bodybuilders will stack DECAMED 250 (Nandrolone Decanoate) with similar oral bulking compounds. This is typically an oral anabolic steroid, such as DIANAMED 10 (Methandienone), WINIMED 10 (Stanazolol), ANADROMED 50 (Oxymethelone), ANAVAMED 10 (Oxandrolone), etc. However, for the purposes of bulking and strength gaining, most individuals tend to lean towards compounds generally suitable for these goals, such as Anadrol (Oxymetholone) or DIANAMED 10 (Methandienone) for the first 4 – 6 weeks. These compounds are used because of the mass-adding properties that lend themselves to DECAMED 250 (Nandrolone Decanoate) and Testosterone quite well.

During his early career as a bodybuilder, Arnold Schwarzenegger's favorite stack was a DIANAMED 10 (Methandienone) and DECAMED 250 (Nandrolone Decanoate). This cycle is one of the most popular bulking stacks ever.

Another typical age-old cycle stack of Testosterone / DECAMED 250 (Nandrolone Decanoate)  / DIANAMED 10 (Methandienone) is often discussed. The Testosterone/Nandrolone/DIANAMED 10 (Methandienone) stack was originally devised, pioneered, and popularized by the golden era bodybuilders of the 1960s and 1970s. It is often recommended for all tiers of users (beginners, intermediates, and advanced) as it is a timeless stack that will provide quality gains to any user no matter the experience.

Dosages and Administration of DECAMED 250 (Nandrolone Decanoate)

As a prescription drug, DECAMED 250 (Nandrolone Decanoate) as originally recommended to be prescribed at a dosage of 50 – 100mg every 3 – 4 weeks, for no longer than 12 weeks. Every medical condition, disability or disease is different, therefore the prescription recommendations for DECAMED 250 (Nandrolone Decanoate) is individual according to every patient’s needs. For example, anemic patients were prescribed 100 – 200mg per week, a DECAMED 250 (Nandrolone Decanoate) dosage that is considerably larger than the common prescription doses.

The usual dosage of DECAMED 250 (Nandrolone Decanoate) for physique or performance-enhancing purposes is usually used by beginners in the range of 300 – 500mg per week. Intermediate users normally do not have to venture above the 500mg mark within that beginner range, especially when DECAMED 250 (Nandrolone Decanoate) is stacked with other compounds such as Testosterone and/or another oral compound as a Kickstarter. Advanced users also can use this dose range, but should an advanced user require a higher dose to elicit gains, a range of approximately 600 – 800mg or greater should suffice, especially if Nandrolone is the primary anabolic compound of a cycle and Testosterone is simply run as a supportive compound at TRT (Testosterone Replacement Therapy) doses.


Chemical info /  Information
Nandrolone (AKA Deca, Deca Durabolin, Nandrolone Decanoate, Nandrolone Phenylpropionate)
Chemical Name: 19-norandrost-4-en-3-one-17beta-ol, 17β-Hydroxyestra-4-en-3-one
Molecular Weight: 274.40 g/mol
Formula: C18H26O2
Original Manufacturer: Organon
Elimination half-life: 15 days
Detection Time: 17 – 18 months
Anabolic Rating: 125
Androgenic Rating: 37