Sibutramin 20 mg
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- Brand: ASTERA LABS
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- Model: AL SIBUTRAMINE
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What is Sibutramine 20 (Astera Labs)?
Sibutramine suppresses appetite more strongly than most things sold for the purpose. It also raises blood pressure and heart rate, and that is what decides whether it suits you.
Also sold as Reductil, Meridia, Sibutrex or sibutramine hydrochloride.
Sibutramine blocks the reuptake of serotonin and noradrenaline, which is the same broad mechanism as some antidepressants. The effect people take it for is a marked reduction in appetite and a small rise in metabolic rate. The same noradrenaline activity is what raises blood pressure and heart rate, which is where the problem lies.
Sibutramine benefits
- Strong appetite suppression, stronger than most things sold for the purpose
- Small increase in metabolic rate alongside the appetite effect
- Once daily dosing
- Effective in clinical trials at producing weight loss while taken
Sibutramine dosage
- Standard
- 10mg once daily
- Higher end
- 15mg once daily
- These tablets
- 20mg each, so most people should take half
- Frequency
- Once daily, morning
- Duration
- Short blocks, and not alongside stimulants
The usual dose is 10 to 15mg and these tablets are 20mg. Most people should split them rather than take a whole one, and start at half.
Take it in the morning. Taken later it interferes with sleep, and poor sleep works directly against the fat loss you are taking it for.
Package content
- Tablets
- 50 per sachet
- Strength
- 20mg sibutramine per tablet
- Sibutramine per sachet
- 1000mg
- Usual dose range
- 10 to 15mg daily
- Brand
- Astera Labs
At 10mg a day, half a tablet, one sachet covers 100 days.
Store below 30°C. Protect from light. Do not freeze. Keep out of reach of children.
Who is Sibutramine for?
People for whom appetite is the thing that repeatedly ends a diet, and who have normal blood pressure, a normal resting heart rate and no cardiovascular history.
It is the wrong purchase for anyone on cycle with elevated blood pressure, anyone already taking a stimulant fat burner, and anyone with any heart history at all.
How to use Sibutramine
Swallow in the morning with water. The usual dose is 10 to 15mg and these are 20mg tablets, so most people should take half and assess from there. Do not take it in the afternoon or evening.
Frequently asked questions
Why does it raise blood pressure?
Because the same noradrenaline activity that kills your appetite also tightens blood vessels and speeds the heart up. Both effects come from one mechanism, so you cannot have the appetite suppression without some of the cardiovascular effect.
How much varies a lot between people, which is exactly why measuring beats assuming. A home monitor costs very little and tells you within a week whether this suits you.
Can I take it with a stimulant fat burner?
No. That is the combination most likely to cause harm. Sibutramine raises blood pressure and heart rate through noradrenaline, and stimulant fat burners do the same thing through the same system.
Adding a steroid cycle on top, which raises blood pressure independently, stacks three pressures on one cardiovascular system. Pick one at most.
Why are the tablets stronger than the clinical dose?
The dose used in trials was 10 to 15mg daily, and these tablets are 20mg. That is above the range the evidence was built on.
Split them. Starting at half a tablet gives you 10mg, which is the standard starting dose, and it lets you find out how it affects your blood pressure before committing to more.
Does it actually work?
Yes, while you take it. Appetite suppression is genuine and often marked, and trials showed real weight loss against placebo.
The weight tends to return when it stops, because nothing about the underlying eating pattern has changed. It buys you a window rather than solving the problem.
What should I not take it with?
SSRIs, SNRIs, MAOIs and triptans are the important ones, because combining serotonergic drugs risks serotonin syndrome, which is a medical emergency.
Also avoid stimulant fat burners, and be cautious with anything else raising blood pressure. If you are on an antidepressant, this compound is not for you.