What is MK677 10 (Astera Labs)?
Astera Labs ibutamoren in 10mg tablets, 50 to a sachet. Growth hormone from a tablet, with no suppression and no PCT.
Also sold as ibutamoren, MK-677 or Nutrobal.
MK-677 works differently from most of this category. It is a growth hormone secretagogue: it tells your pituitary to release growth hormone, the same mechanism as the injectable secretagogues, but in a tablet with a long enough half-life to work once a day. That is why it does not suppress testosterone.
MK677 (Astera) benefits
- Raises growth hormone and IGF-1 from a tablet rather than an injection
- Does not suppress testosterone, because it does not act on androgen receptors
- No post-cycle therapy needed, which is genuinely unusual in this category
- Marked improvement in sleep depth, which is what most users notice first
- Long half-life, so one dose a day is the whole protocol
- 10mg tablets, 50 to a sachet
MK677 dosage
- Standard
- 10 to 25mg per day
- Common
- 10mg, one tablet
- Timing
- Before bed, which suits the sleep effect
- Frequency
- Once daily
- Half-life
- About 24 hours
- Run length
- 8 to 16 weeks
10mg is where most people sit and 25mg is the upper end. Higher doses mostly add water retention and hunger rather than more growth hormone.
Taken before bed, which suits both the sleep effect and the early lethargy.
Package content
- Tablets
- 50 per sachet
- Strength
- 10mg ibutamoren per tablet
- Ibutamoren per sachet
- 500mg
- Half-life
- About 24 hours
- Brand
- Astera Labs
At 10mg a day one sachet covers 50 days.
Store below 30°C. Protect from light. Do not freeze. Keep out of reach of children.
Who is MK677 (Astera) for?
People who want growth hormone benefits without injecting, and anyone struggling to eat enough on a bulk.
MK677 10 is the same strength from Deus Medical, and the Biaxol capsules add black pepper extract for absorption.
Before you run it. The hunger is substantial, arrives within days and does not fade much over a run. That is excellent on a bulk and works against you on a cut, so pick your phase for it. Some water retention and puffiness are normal and settle when you come down, as does the mild lethargy some people get in the first fortnight. Growth hormone nudges blood sugar upward, so if you are prediabetic it is worth keeping an eye on. It does not suppress testosterone and needs no post-cycle therapy.
Fasting glucose and IGF-1 are the two numbers worth tracking. Not for anyone under 18, and not for women who are pregnant or breastfeeding.
How to use MK677 (Astera)
Swallow one tablet with water before bed, with or without food.
Frequently asked questions
How is MK-677 different from the other compounds here?
It works on growth hormone rather than on androgen receptors, which is why the effects feel different: sleep, appetite and recovery rather than a direct push on muscle tissue.
The practical upside is that it does not suppress your own testosterone, so there is no post-cycle protocol to run afterwards. That is unusual in this category.
Does it need PCT?
No, and it is the one compound in this category where that answer is genuinely no. MK-677 does not act on androgen receptors and does not suppress your own testosterone.
It does raise growth hormone and IGF-1, which your body adjusts to, but there is nothing for a SERM to restart.
Why am I so hungry on it?
Because it mimics ghrelin, which is the hunger hormone. The appetite effect is not a side effect of the mechanism, it is the mechanism working.
It arrives within days and does not fade much over a run. Excellent if you are struggling to eat enough, very difficult if you are dieting.
Does it affect blood sugar?
Yes, and this is the effect that actually matters over a long run. Growth hormone opposes insulin, so fasting glucose tends to rise and insulin sensitivity falls.
For most people at 10mg it is minor. Over months, or if you are already prediabetic, it is not. Test rather than assume.
How long until it works?
Sleep usually changes within the first week and is the most reliable early sign. Appetite arrives just as fast.
Anything to do with body composition takes months, the same as growth hormone itself. This is not a compound to judge at week four.
